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Scienze biochimiche "A. Rossi Fanelli" >
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|Title: ||identification of molecular targets in the human genome|
|Authors: ||LEONI, GUIDO|
|Tutor: ||Tramontano, Anna|
|Keywords: ||alternative splicing|
|Issue Date: ||2012|
|Abstract: ||The purpose of the present study is to contribute to the field of functional genomics by developing, testing and applying computational methods to the problem of the evaluation of the effects of environmental and pharmacological molecules on genome expression.
Original results are described in four independent sections
The first two sections are devoted to the investigation of the coding potential of alternative splicing products in the human genome.
Sections three and four are devoted to the application of computational techniques to investigate the molecular targets and the effects on their expression of molecules known to interfere with the physiological functions
of a cell. In particular these techniques were applied on a class of compounds (tocotrienols) constituents of the Vitamin E.|
|Research interests: ||Bioinformatics, biochemistry, computational biology applied to nutrition|
|Personal skills keywords: ||perl programmer|
skills in analysis of transcriptomic expression data
|Appears in PhD:||BIOCHIMICA|
Files in This Item:
|TesiGuidoLeonicopiaelettronica.pdf||Tesi Dottorato in Biochimica||7.86 MB||Adobe PDF|
File del Curriculum Vitae:
|CurriculumVitae.doc|| ||70.21 kB||Microsoft Word|
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